Endocrine Abstracts

Background: Diabetic ketoacidosis (DKA) has been associated with severe hemolysis in patients with Glucose-6-phosphate dehydrogenase (G6PD) deficiency after restoration of euglycemia. Less than 30 cases have been reported so far. The exact mechanism is not fully understood.Case presentation: A 35-year-old African American man presented to the emergency department with polyuria, polydipsia, abdominal pain and weight loss the last 15 days. Physical examina...

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with multisystem involvement and varied presentation but its association with adrenal insufficiency is rarely reported.Case presentation: A 30-year-old female presented to the emergency department with fever, lethargy and syncopal episodes during the last 48 h. She complained of general weakness, abdominal pain, nausea, vomiting, weight loss and anorexia for five months. Symptoms det...

Aim: To explore the epidemiological characteristics and symptoms of psychological distress of well-controlled endocrine patients without a diagnosis of a psychiatric disorder attending the Endocrine outpatient clinic of the University Hospital, Heraklion, Crete, Greece during the COVID-19 pandemic. Methods: Eighty-four patients participated by completing questionnaires about demographics, endocrine diagnosis, covid infection, preventive measures, vaccination s...

Background: Psychological distress is elevated during pandemics such as the COVID-19 outbreak both in health care professionals and patients.Aim: To compare worries about the COVID-19 pandemic, need and sources of information, and psychological distress between endocrinology patients and staff at an outpatient department of the University Hospital, Heraklion, Crete, GreeceMethods: One hundred and four patients and sixty members of ...

Background: Acromegaly is a rare endocrine disorder due to growth hormone excess attributed to a pituitary tumor, in most cases. Epidemiological data of acromegaly are derived from national tumor registries or population studies while there are no published data in the Greek population except for a few small studies regarding treatment outcome.Methods: We carried out a retrospective ongoing observational study to determine the epidemiology, presentation ...

BackgroundPheochromocytomas (PHOEs) and paragangliomas (PGLs) are rare neuroendocrine tumors originating from chromaffin cells. PHEO/PGL incidence ranges between 2–8/million, with 10–49% of these tumors being detected incidentally during imaging performed for other reasons. Up to 40% of PHEOs/PGLs patients have disease-specific germline pathogenic variants. This study aimed to investigate the epidemiology, clinical course, and genetic backgroun...